Biblio
Found 13 results
Filters: Author is Li, Y. [Clear All Filters]
The catalytic mechanism of the RNA methyltransferase METTL3. eLife. 12:RP92537.
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2024. Structure-based design of a potent and selective YTHDC1 ligand. Journal of Medicinal Chemistry. 67(11):9516-9535.
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2024. Structure-Based Design of CBP/EP300 Degraders: When Cooperativity Overcomes Affinity. Journal of the American Chemical Society Au. 4(9):3466-3474.
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2024. Ginkgolic acids inhibit SARS-CoV-2 and its variants by blocking the spike protein/ACE2 interplay. International Journal of Biological Macromolecules. 226:780-792.
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2023. Structure-Based Design of inhibitors of the m6A‑RNA writer enzyme METTL3. ACS Bio & Med Chem Au. 3(4):359–370.
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2023. Fragment ligands of the m6A-RNA reader YTHDF2. ACS Medicinal Chemistry Letters. 13(9):1500-1509.
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2022. Structure-based design of ligands of the m6A-RNA reader YTHDC1. European Journal of Medicinal Chemistry Reports. 5:100057.
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2022. Atomistic and thermodynamic analysis of N6-methyladenosine (mA) recognition by the reader domain of YTHDC1. Journal of Chemical Theory and Computation. 17(2):1240-1249.
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2021. Dynamic 3D proteomes reveal protein functional alterations at high resolution in situ. Cell. 184(2):545-559.e22.
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2021. METTL3 inhibitors for epitranscriptomic modulation of cellular processes. ChemMedChem. 16(19):3035-3043.
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2021. Selectively disrupting m6A-dependent protein-RNA interactions with fragments. ACS Chemical Biology. 15(3):618-625.
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2020. Structural and dynamic insights into redundant function of YTHDF proteins. Journal of Chemical Information and Modeling. 60(12):5932-5935.
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2020. Flexible binding of m6A reader protein YTHDC1 to its preferred RNA motif. Journal of Chemical Theory and Computation. 15(12):7004-7014.
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2019.