Biblio

Found 13 results
Filters: Author is Li, Y.  [Clear All Filters]
2024
Corbeski I., Vargas-Rosales P.A, Bedi R.K, Deng J., Coelho D., Braud E., Iannazzo L., Li Y., Huang D., Ethève-Quelquejeu M. et al..  2024.  The catalytic mechanism of the RNA methyltransferase METTL3. eLife. 12:RP92537.
Zálešák F., Nai F., Herok M., Bochenkova E., Bedi R.K, Li Y., Errani F., Caflisch A..  2024.  Structure-based design of a potent and selective YTHDC1 ligand. Journal of Medicinal Chemistry. 67(11):9516-9535.
Cheng-Sánchez I., Gosselé K., Palaferri L., Laul E., Riccabella G., Bedi R.K, Li Y., Müller A., Corbeski I., Caflisch A. et al..  2024.  Structure-Based Design of CBP/EP300 Degraders: When Cooperativity Overcomes Affinity. Journal of the American Chemical Society Au. 4(9):3466-3474.
2023
Xiang Y., Zhai G., Li Y., Wang M., Chen X., Wang R., Xie H., Zhang W., Ge G., Zhang Q. et al..  2023.  Ginkgolic acids inhibit SARS-CoV-2 and its variants by blocking the spike protein/ACE2 interplay. International Journal of Biological Macromolecules. 226:780-792.
Bedi R.K, Huang D., Li Y., Caflisch A..  2023.  Structure-Based Design of inhibitors of the m6A‑RNA writer enzyme METTL3. ACS Bio & Med Chem Au. 3(4):359–370.
2022
Nai F., Nachawati R., Zálešák F., Wang X., Li Y., Caflisch A..  2022.  Fragment ligands of the m6A-RNA reader YTHDF2. ACS Medicinal Chemistry Letters. 13(9):1500-1509.
Li Y., Bedi R.K, Nai F., von Roten V., Dolbois A., Zálešák F., Nachawati R., Huang D., Caflisch A..  2022.  Structure-based design of ligands of the m6A-RNA reader YTHDC1. European Journal of Medicinal Chemistry Reports. 5:100057.
2021
Li Y., Bedi R.K, Wiedmer L., Sun X., Huang D., Caflisch A..  2021.  Atomistic and thermodynamic analysis of N6-methyladenosine (mA) recognition by the reader domain of YTHDC1. Journal of Chemical Theory and Computation. 17(2):1240-1249.
Cappelletti V., Hauser T., Piazza I., Pepelnjak M., Malinovska L., Fuhrer T., Li Y., Dörig C., Boersema P, Gillet L. et al..  2021.  Dynamic 3D proteomes reveal protein functional alterations at high resolution in situ. Cell. 184(2):545-559.e22.
Moroz-Omori E.V, Huang D., Bedi R.K, Cheriyamkunnel S.J, Bochenkova E., Dolbois A., Rzeczkowski M.D, Li Y., Wiedmer L., Caflisch A..  2021.  METTL3 inhibitors for epitranscriptomic modulation of cellular processes. ChemMedChem. 16(19):3035-3043.
2020
Bedi R.K, Huang D., Wiedmer L., Li Y., Dolbois A., Wojdyla J.A, Sharpe M.E, Caflisch A., Śledź P..  2020.  Selectively disrupting m6A-dependent protein-RNA interactions with fragments. ACS Chemical Biology. 15(3):618-625.
Li Y., Bedi R.K, Moroz-Omori E.V, Caflisch A..  2020.  Structural and dynamic insights into redundant function of YTHDF proteins. Journal of Chemical Information and Modeling. 60(12):5932-5935.
2019
Li Y., Bedi R.K, Wiedmer L., Huang D., Śledź P., Caflisch A..  2019.  Flexible binding of m6A reader protein YTHDC1 to its preferred RNA motif. Journal of Chemical Theory and Computation. 15(12):7004-7014.