Biblio
Found 5 results
Filters: Keyword is Drug Design and Author is Spiliotopoulos, D. [Clear All Filters]
Ligand retargeting by binding site analogy. European Journal of Medicinal Chemistry. 175:107-113.
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2019. Virtual screen to NMR (VS2NMR): Discovery of fragment hits for the CBP bromodomain. Bioorganic & Medicinal Chemistry Letters. 27(11):2472-2478.
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2017. Fragment-based design of selective nanomolar ligands of the CREBBP bromodomain. Journal of Medicinal Chemistry. 59(4):1350-1356.
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2016. Fragment-based in silico screening of bromodomain ligands. Drug Discovery Today. Technologies. 19:81-90.
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2016. Molecular dynamics simulations of bromodomains reveal binding-site flexibility and multiple binding modes of the natural ligand acetyl-lysine. Israel Journal of Chemistry. 54(8-9):1084–1092.
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2014.