• Jonas Wepfer is currently a Ph.D. Student in the Caflisch group.

    Mission Statement:

    I graduated from the ETH in Zurich with a Master’s degree in biological chemistry. During my studies I was especially interested in understanding protein protein interactions and how the function of proteins can be mediated through their structure. This led me first to the University of Bern where I worked in the laboratory of Prof. Jin Li on a novel autoantibody which upon binding to the ion channel KCNQ1 would change its properties. I then moved to Sydney to work in the group of Prof. David James in the field of insuline resistance. The project I was working on aimed at understanding at a structural level the role played by PDE3B and ABHD15 in the signalling cascade leading to the inhibition of lipolysis in adipocytes. Back in Switzerland I wanted to continue to work on my Master’s thesis project but with a new computational approach. A collaboration between the laboratories of Prof. Andreas Plückthun and Prof. Amedeo Caflisch made it possible. I started my PhD in the beginning of 2021 and will be working on using computational methods to analyse designed armadillo repeat proteins in order to develop novel peptide binders.

    Jonas Wepfer has been a member of the Caflisch group from 01/2021 - current.

    Email address:

    j [dot] wepfer [at] bioc [dot] uzh [dot] ch