Bedi, R. K., & Caflisch, A. (2026). A DNA-Based Binding Assay for the m6A-RNA Reader Proteins. Chembiochem, 27(6), e202500897. https://doi.org/10.1002/cbic.202500897 (Original work published)
Vargas-Rosales, P. A., Giangreco, G., & Caflisch, A. (2025). Disrupting Amyloid Filaments of Tau by Means of Electric Fields. The Journal of Physical Chemistry B, 129(36), 9124-9137. https://doi.org/10.1021/acs.jpcb.5c04393 (Original work published)
Xiang, Y., Zhai, G., Li, Y., Wang, M., Chen, X., Wang, R., … Chen, L. (2023). Ginkgolic acids inhibit SARS-CoV-2 and its variants by blocking the spike protein/ACE2 interplay. International Journal of Biological Macromolecules, 226, 780-792. https://doi.org/10.1016/j.ijbiomac.2022.12.057 (Original work published)
Dehabadi, M. H., Caflisch, A., Ilie, I. M., & Firouzi, R. (2022). Interactions of curcumin’s degradation products with the Aβ dimer: a computational study. The Journal of Physical Chemistry B, 126(39), 7627-7637. https://doi.org/10.1021/acs.jpcb.2c05846 (Original work published)
Lee, J.-H., Wang, R., Xiong, F., Krakowiak, J., Liao, Z., Nguyen, P. T., … Li, W. (2021). Enhancer RNA m6A methylation facilitates transcriptional condensate formation and gene activation. Molecular Cell, 81(16), 3368-3385.e9. https://doi.org/10.1016/j.molcel.2021.07.024 (Original work published)
Pohl, M. O., Busnadiego, I., Marrafino, F., Wiedmer, L., Hunziker, A., Fernbach, S., … Stertz, S. (2021). Combined computational and cellular screening identifies synergistic inhibition of SARS-CoV-2 by lenvatinib and remdesivir. Journal of General Virology, 102(7). https://doi.org/10.1099/jgv.0.001625 (Original work published)
Spiliotopoulos, D., Wamhoff, E.-C., Lolli, G., Rademacher, C., & Caflisch, A. (2017). Discovery of BAZ2A bromodomain ligands. European Journal of Medicinal Chemistry, 139, 564-572. https://doi.org/10.1016/j.ejmech.2017.08.028 (Original work published)
Langini, C., Caflisch, A., & Vitalis, A. (2017). The ATAD2 bromodomain binds different acetylation marks on the histone H4 in similar fuzzy complexes. The Journal of Biological Chemistry, 292(40), 16734-16745. https://doi.org/10.1074/jbc.M117.786350 (Original work published)
Marchand, J.-R., Lolli, G., & Caflisch, A. (2016). Derivatives of 3-amino-2-methylpyridine as BAZ2B bromodomain ligands: In silico discovery and in crystallo validation. Journal of Medicinal Chemistry, 59(21), 9919-9927. https://doi.org/10.1021/acs.jmedchem.6b01258 (Original work published)
Roos, M., Pradère, U., Ngondo, R. P., Behera, A., Allegrini, S., Civenni, G., … Hall, J. (2016). A small-molecule inhibitor of Lin28. ACS Chemical Biology, 11(10), 2773-2781. https://doi.org/10.1021/acschembio.6b00232 (Original work published)