%0 Journal Article %K Computer Simulation %K Animals %K Antineoplastic Agents %K Cell Line, Tumor %K Crystallography, X-Ray %K Drug Screening Assays, Antitumor %K Humans %K Molecular Docking Simulation %K Receptor, EphA3 %K Receptor, EphB4 %K Structure-Activity Relationship %K Protein Binding %K Mice %K Cell Line %K Cell Membrane Permeability %K Cricetinae %K High-Throughput Screening Assays %K Molecular Dynamics Simulation %K Cricetulus %K Phosphorylation %B Journal of Medicinal Chemistry %D 2013 %G eng %N 1 %P 84-96 %R 10.1021/jm301187e %T Optimization of inhibitors of the tyrosine kinase EphB4. 2. Cellular potency improvement and binding mode validation by X-ray crystallography %V 56 %1 0168 %8 2013 Jan 10 %9 Research Article