%0 Journal Article
%K Computer Simulation
%K Hydrogen Bonding
%K Kinetics
%K Models, Molecular
%K Protein Structure, Secondary
%K Crystallography, X-Ray
%K Humans
%K Oligopeptides
%K Protein Conformation
%K Amino Acid Sequence
%K Molecular Sequence Data
%K Aspartic Acid Endopeptidases
%K Binding Sites
%K Water
%K Amyloid Precursor Protein Secretases
%K Endopeptidases
%K Alzheimer Disease
%K Tyrosine
%K Temperature
%K Enzyme Inhibitors
%K Substrate Specificity
%K Amyloid beta-Protein Precursor
%K Asparagine
%K Catalysis
%K Protons
%K Serine
%B Structure
%D 2005
%G eng
%N 10
%P 1487-1498
%R 10.1016/j.str.2005.06.015
%T Functional plasticity in the substrate binding site of beta-secretase
%V 13
%1 0071
%8 2005 Oct
%9 Research Article