Biblio
Found 8 results
Filters: Keyword is High-Throughput Screening Assays and Author is Caflisch, A. [Clear All Filters]
A reader-based assay for m6A writers and erasers. Analytical Chemistry. 91(4):3078-3084.
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2019. High-throughput fragment docking into the BAZ2B bromodomain: Efficient in silico screening for X-Ray crystallography. ACS Chemical Biology. 11(3):800-807.
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2016. Discovery of BRD4 bromodomain inhibitors by fragment-based high-throughput docking. Bioorganic & Medicinal Chemistry Letters. 24(11):2493-2496.
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2014. Discovery of ZAP70 inhibitors by high-throughput docking into a conformation of its kinase domain generated by molecular dynamics. Bioorganic & Medicinal Chemistry Letters. 23(20):5721-5726.
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2013. Optimization of inhibitors of the tyrosine kinase EphB4. 2. Cellular potency improvement and binding mode validation by X-ray crystallography. Journal of Medicinal Chemistry. 56(1):84-96.
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2013. High-throughput virtual screening using quantum mechanical probes: Discovery of selective kinase inhibitors. ChemMedChem. 5(7):1007-1014.
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2010. Library screening by fragment-based docking. Journal of Molecular Recognition. 23(2):183-193.
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2010. Quantum mechanical methods for drug design. Current Topics in Medicinal Chemistry. 10(1):33-45.
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2010.